Figure 3
From: Protein methylation is required to maintain optimal HIV-1 infectivity
TEM of infected CEM cells. Control (A top panel, B, and C) or AdOx-treated HIV-1 infected CEM (A bottom panel, D E, and F) were thin sectioned and examined by TEM. A) Viewed at 100,000 × showing typical HIV-1 assembly structures. B and C) Viewed 100,000 × and 50,000 ×, respectively, show HIV-1 that are primarily ~100 nm in diameter. A large HIV particle (~150 nm) observed in control sections is indicated by an arrow in B. D) Viewed at 50,000 × shows many typical HIV-1 particles. Two larger virus particles with a diameter of ~150 to ~180 nm are depicted by the arrows. Large HIV-1 particles were present in all sections of AdOx treated cells and two more examples are shown in E and F (both at 100,000 ×). E depicts a particle which appears to contain two core structures.