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Figure 2 | Retrovirology

Figure 2

From: Second site escape of a T20-dependent HIV-1 variant by a single amino acid change in the CD4 binding region of the envelope glycoprotein

Figure 2

Replication of the T20-dependent GIA-SKY mutant and the GIA-SKY-G431R revertant virus. Molecular clones were transfected in SupT1 cells that were cultured with (100 ng/ml) and without T20. Virus replication curves were made over a 7-day period. Closed circles represent the original GIA-SKY mutant virus and open circles the GIA-SKY-G431R revertant. This is a representative experiment, similar results were observed in 3 repeated experiments including results in figure 4, top.

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