HIV infected CD4 T cell (reservoir cells) in rhesus macaques vaccinated with Tat Oyi (panel A) and control macaques vaccinated with β-gal (panel B) following SHIV challenge. The 965 (white square), 966 (no symbol), 969 (black circle), 975 (black square), 9611 (white circle), 9711 (white triangle) and 9712 (black triangle) Macaques are the Tat Oyi vaccinated Macaques. The 963 (white square), 964 (black square), 978 (white circle) and 9610 (black circle) Macaques are the controls vaccinated with β-gal. The upper panel shows that no reservoir cells were detectable in the seven Tat Oyi vaccinated macaques after 56 days although macaques 965 and 969 had high viremia peaks (Fig 1). Interestingly, no reservoir cells were detectable at any time for macaque 966 even after its second SHIV challenge.