Figure 1

Three-dimensional structure of the nuclear pore complex. The main components of the pore include the central framework (yellow), the cytoplasmic ring moiety and attached filaments (blue), the nuclear ring moiety and the distal ring of the nuclear basket (orange). Nuclear membranes are depicted in grey. Reproduced with permission from Fahrenkrog B and Aebi U, Nature Reviews Molecular Cell Biology 4: 757–766 (2003) Macmillan Magazines Ltd.