Figure 2

Estimated number of non-synonymous substitutions along the HIV-1 Env V1–V5 fragment sequenced, estimated in Datamonkey. Results are presented cumulatively for a rapid progressor (infant 1449) and a slow progressor (infant 1984), with the variable loops V1V2, V3, V4 and V5 shaded. The secondary structure elements (α helix and β sheet) are color coded as in Chen et al. [56].