Figure 4

The CypA-dependency of FIV. Jurkat T cells were infected with HIV-1 wild-type (A), FIV wild-type (B), and FIV P90A (C) in the presence or absence of 1.25 μM of CsA. All viruses were first normalized on CRFK cells and equivalent CRFK infectious units were used and are plotted on the X-axis. For example, the amount of virus that gave 20% GFP positive cells on CRFK cells is 0.2 on the X-axis. The infected Jurkat cells were analyzed by flow cytometry and the infectivity is presented as % GFP+ cells.