Figure 7
From: Inhibition of PP2A by LIS1 increases HIV-1 gene expression
LIS1 inhibition of PP2A is not altered by Tat. Phosphatase assay was performed as described in Methods. PP2A (open bars) or PP1 (closed bars) were assayed in the presence of LIS1 and/or Tat. Lane 1, 1 μg of Tat. Lane 2, 0.2 μg of LIS1. Lane 3, 0.4 μg of LIS1. Lane 4, 0.5 μg of Tat and 0.2 μg of LIS1. Lane 5, 0.5 μg of Tat and 0.4 μg of LIS1. Lane 6, 1 μg of Tat and 0.2 μg of LIS1. Lane 7, 1 μg of Tat and 0.4 μg of LIS1.