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Table 1 Summary of the roles of the motifs in MLV and MPMV Env CT in subcellular Env trafficking.

From: The conserved dileucine- and tyrosine-based motifs in MLV and MPMV envelope glycoproteins are both important to regulate a common Env intracellular trafficking

MOTIF (MLV/MPMV) ROLE IN TRAFFICKING EFFECT OF MUTATION
23YHQL26/23YHRL26 Endocytosis Increase plasma membrane localization
23YHQL26/23YHRL26 TGN retrieval Delocalization in unidentified late-endocytic compartments
3LV4/3LM4 Sorting from TGN Delocalization in the endosomal pathway