Figure 4
From: The virion-associated incoming HIV-1 RNA genome is not targeted by RNA interference
Sequence-specific inhibition in shNef-expressing cells. a) Schematic of RNAi-mediated targeting of mRNA with the shNef target sequence (gray box) in shNef-expressing SupT1 cells. b) SupT1 cells stably expressing shNef (+ shNef) or control SupT1 cells (- shNef) were transfected with luciferase reporter constructs that contain the complete shNef target sequence (pGL3-Nef) or not (pGL3-R2). The mean values obtained in two independent experiments are shown. Values measured in the control transfection (- shNef) were set at 100% for each reporter construct.