Figure 4

IN and INI1 but not the components of the SWI/SNF complex are required for efficient HIV-1 particle production. A. IN is required for the complementation of particle production by INI1. Graphic representation of particle-associated p24 antigen (pg/ml) in the MON culture supernatants transfected with either ΔIN Gag-Pol (■) or wild type Gag-Pol (□) along with increasing concentrations of INI1 (average of 2 independent experiments). B. The ATPase components of SWI/SNF complex are not required for HIV-1 particle production. Graphic representation of particle associated p24 released from SW13 and C33A, the two BRG1 and hBRM-dificient cells and 293T cells in the absence (■) or presence (□) of transfected HA-INI1 (average of 3 independent experiments).