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Figure 2 | Retrovirology

Figure 2

From: The predominance of Human Immunodeficiency Virus type 1 (HIV-1) circulating recombinant form 02 (CRF02_AG) in West Central Africa may be related to its replicative fitness

Figure 2

Relative replicative fitness (W) in activated T cells. Dot plots represent the results of growth competitions in PHA/IL-2 activated PBMC (10 CRF02_AG, 5 subtype A and 5 subtype G). Red dots represent competitions between CRF02_AG and subtype A viruses; green dots show competitions between CRF02_AG and subtype G. An open symbol indicates that the CRF02_AG virus is X4-tropic, whereas solid symbols represent competitions with R5-tropic CRF02_AG viruses (irrespective of the coreceptor tropism of the subtype A and G isolates). The competitions with CRF02_AG viruses from patients with AIDS (CD4+ cells <200 cells/Ī¼l) are shown at the left hand side and the competitions with CRF02_AG viruses from non-AIDS patients at the right hand side, again irrespective of the CD4+ T cell counts in the patients from which the competing A or G virus was derived.

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