Skip to main content
Figure 3 | Retrovirology

Figure 3

From: Wild-type and central DNA flap defective HIV-1 lentiviral vector genomes: intracellular visualization at ultrastructural resolution levels

Figure 3

Quantification of intracellular vector genome detection. (A) Electron micrograph of control non-transduced cells showing minimal background signal. (B) DNA hybridization signals from 4 independent cell population infections were counted and represented as total nuclear over cytoplasmic signal ratio. All cell areas containing DNA hybridization signal were systematically photographed (about 150–200 photos) and signal was carefully quantified, each time with equal surface of nuclear and cytoplasmic compartments. The p value (Mann-Whitney test) shows the results are highly statistically relevant.

Back to article page

Retrovirology

ISSN: 1742-4690

Contact us