Skip to main content

Table 2 Lymphocyte subsets and activation markers in the EUs and UCs

From: Reduced CD4 T cell activation and in vitro susceptibility to HIV-1 infection in exposed uninfected Central Africans

Lymphocyte subsets EUs (n = 25) UCs (n = 24) p-value°
Lymphocytes * 2500 (2052–3031) 2184 (1800–2632) 0.26
CD3 (%)* 72 (69–77) 73 (70–80) 0.27
CD4 (%)* 42 (32–46) 42 (34–45) 0.98
CD8 (%)* 28 (23–33) 28 (25–33) 0.63
NK (%)* 17 (13–22) 14 (11–18) 0.19
T cell markers
(T cell subset) #
   
HLA-DR (CD4+)* 138.6 (61–208) 288.7 (217–403) 0.0001
CD38 (CD4+)* 527.6 (267 – 862) 269.5 (238–410) 0.13
HLA-DR (CD8+)* 200 (124–285) 280.1 (165–360) 0.13
CD38 (CD8+)* 370 (194–527) 312.3 (244–441) 0.87
CXCR4 (CD4+)* 1041 (475–1233) 579.2 (221–895) 0.11
CCR5 (CD4+)* 44.1 (26.9–88.7) 146.5 (92.4–312) 0.0001
CXCR4 (CD8+)* 470.2 (298–747) 323.2 (155–500) 0.17
CCR5(CD8+)* 250.5 (164–293) 169.3 (106–245) 0.20
  1. * Median (Q1–Q3)
  2. ° Mann-Whitney U test. After Bonferroni correction the level of significance was set at 0.004
  3. # Absolute values