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Table 2 IC50 values of Rgp41A and T-20 on the entry of adapted HIV-1 isolates into PBL.

From: Antiviral properties of two trimeric recombinant gp41 proteins

 

Rgp41A

T-20

 

μg/ml

nM

μg/ml

nM

LAI

16a

356

/

/

NDK

14.5

322

0.38

84

YU2

NEb

NE

1.05

233

  1. aThese values represent the amount of recombinant proteins giving a 50% reduction of the amount of p24 in cell extracts, compared to the value in the absence of inhibitor and correspond to the mean value of a typical experiment. IC50 in nM correspond to the trimeric form of Rgp41A. bNE: No effect.
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Retrovirology

ISSN: 1742-4690

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