| | Rgp41A | Rgp41B | T-20 |
---|
| | μg/ml | nM | μg/ml | nM | μg/ml | nM |
---|
Pseudotyped
| LAI | 2.5a | 56 | 18 | 429 | / | / |
| ADA | 7 | 156 | NE | NE | / | / |
Laboratory-adapted
| LAI | 13 | 289 | 42* | 1000 | 0.05 | 11 |
| NDK | 38* | 844 | 70* | 1667 | 0.04 | 9 |
| YU2 | 22 | 489 | NE | NE | 2 | 444 |
| ADA | NEb | NE | NE | NE | 1.75 | 389 |
- aThese values correspond to the amount of recombinant proteins resulting in a 50% decrease in reporter activity compared to the value in the absence of inhibitor. Luciferase and β-Galactosidase were used as reporters of infection in the case of pseudotyped viruses and laboratory-adapted strains, respectively. This table shows the averages of a typical experiment performed in duplicate. *: Estimated from exponential regression analysis. bNE:No effect.