Figure 6
From: Silencing of human T-cell leukemia virus type I gene transcription by epigenetic mechanisms
Histone modifications in ATL cell lines. Acetylation of histone was analyzed in tax gene-expressing (ATL-48T) and non-expressing (ATL-43T) cell lines by ChIP assays with anti-acetyl-Histone H3 or H4 (A and B) at four different regions (for 5'-LTR, env, pX and 3'-LTR) of the provirus. Representative data has been shown in A. W.C.E.: whole cell extract. ChIP assay was performed three times and quantified as described in Methods. Values are means ± SD(B). *:p < 0.002.