Figure 2

Phylogenetic analysis of the PEX1-ODAG intergenic region in 9 mammal species. Flanking black boxes correspond to the 24^th exon and the 5^th exon of the PEX1 and ODAG genes, respectively. LTR elements are depicted as red boxes (MaLR-e1 LTR), green boxes (ERV-P LTR) and empty boxes (ERVWE1 and ERV-H proviruses). The ERVWE1 provirus is labeled W, ERV-H Platyrrhini and Catarrhini lineage specific proviruses are labeled H(p) and H(c), respectively. env smaller boxes refer to the ERVWE1 env gene. Proposed ancestral chromosomal structure are drawn in grey cartouches. The cross-box within the H(c) ancestor represents a pol/env deletion as referenced to the HERV-H repbase consensus. Dash lines represent the evolutionary processes leading to Cercopitheque vs. Hominoid lineages. The double slashes indicate the truncation of longest sequences. Clades are derived from previous phylogeny [23] and branches are not drawn to scale.