Phosphatidylserine treatment relieves the block to retrovirus infection of cells expressing glycosylated virus receptors

Table 1 PS treatment allows infection of cells expressing glycosylation-blocked retrovirus receptors^a

Target cells	Vector	PS treatment	Vector titer (AP⁺ FFU/ml)
NIH 3T3	RD114	-	<1
	RD114	+	2.3 × 10⁴
CHO-K1	MoMLV	-	<5
	MoMLV	+	2.3 × 10³

^a Virus infections and PS preparation were performed as described in Materials and Methods. Where indicated, cells were treated with 400 μM PS for 24 h. Data shown are the averages of three independent experiments, each done in duplicate. Values from different experiments varied no more than three-fold.

ISSN: 1742-4690