PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein is essential for the interleukin 2 independent growth induction of a T-cell line

Table 1 Characterization of Tax1, Tax2B, and their mutants

	Tax	Tax△C	Tax351A	Tax353A	Tax2B	Tax2B+C
IL-2 independent proliferation of CTLL-2	+	-	-	-	-	-
% Outgrowth	30–40	3–5	2–5	1–4	0	0
Dlg binding^#	++	-	-	-	-	++
CFSA of Rat-1^#	+++	+	+	+	+	+++

ISSN: 1742-4690