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Figure 6 | Retrovirology

Figure 6

From: Ku protein as a potential human T-cell leukemia virus type 1 (HTLV-1) Tax target in clastogenic chromosomal instability of mammalian cells

Figure 6

Reduced constitutive expression of Ku80 in MT-4 and C81-6645 (C81) cells compared to Jurkat cells. Total cell lysates were prepared from the indicated cell lines and probed with anti-serum which recognizes both Ku70 and 80 proteins. Where indicated the cells were also treated with 1 μM mitomycin C (MMC) for the stated time period before harvesting. Note that constitutively reduced Ku80 expression remains inducible by MMC in the two Tax expressing cell lines (MT-4 and C81).

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