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Table 2 Distribution of proviral load in PBMC and organs of HTLV-I infected rabbits*

From: Quantification of HTLV-I proviral load in experimentally infected rabbits

 

Inoculated with

 

Naked DNA

Cell-free virus

Whole blood

ID (Mo.)

BH19(30)

BH21(30)

BH25(30)

T4-9(11)

BH69(19)

BH76(17)

BH89 (18)

PBMC

7.5

3.9

1.4

6.7

1.3

2.2

8.7

Thymus

22.6

0.4

0.6

0.1

0.3

0.5

1.0

Liver

1.3

0.3

0.3

0.3

0.4

1.8

0.8

Spleen

1.6

0.4

0.1

0.3

0.3

1.7

ND

Skin

23.0

0.3

0.2

4.1

0.2

2.3

0.5

Heart

12.7

2.5

0.3

12.0

0.3

3.1

1.9

Lung

1.8

0.8

0.8

ND

0.7

1.5

2.0

Kidney

3.4

0.5

1.6

0.2

0.5

0.9

1.4

Uterus

3.2

3.0

0.3

ND

1.2

5.0

0.5

Spinal cord

1.7

0.2

0.9

50.5

0.4

0.3

1.2

Brain

0.1

0.3

ND

6.9

ND

ND

ND

Tumor

NA

NA

1.8

1.9

NA

11.0

NA

  1. * Proviral load was reported as copy number per ng of genomic DNA. ND, not determined.
  2. Rabbit identification number (month post inoculation).
  3. Rabbits T4-9 had a uterine leiomyoma, BH76 had benign endometrial dysplasia, and BH25 developed a uterine adenocarcinoma. NA, not applicable.