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Table 1 Comparison of proviral load in HTLV-I infected asymptomatic rabbits and human samples

From: Quantification of HTLV-I proviral load in experimentally infected rabbits

Subjects

Number tested

Copies/ng DNA*

Ref.

Rabbits inoculated with

   

   Naked K30p DNA

5

1.5

 

   BH24 cell-free virus

19

2.8

 

   Whole blood

29

3.7

 

   pSV2 plasmid DNA

1

0

 

Human Asymptomatic carriers

200

1.8

[5]

 

15

1.0†

[36]

 

83

2.7†

[20]

 

120

2.4

[12]

Human HAM/TSP

202

12.0

[5]

 

15

8.8†

[36]

 

9

19.9

[19]

Human ATLL

4

47.4†

[37]

  1. * The mean or median (†) of proviral loads are present as HTLV-I copy number / ng of genomic DNA prepared from PBMC. The rabbits samples were collected after 2 months post inoculation. All published data were converted to this format on the basis of one ng of genomic DNA corresponding to approximately 150 cells.
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Retrovirology

ISSN: 1742-4690

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