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Table 1 Factors that led to consensus that human retroviruses did not exist

From: The discovery of the first human retrovirus: HTLV-1 and HTLV-2

1. Failure to discover them after an extensive survey by many investigators in the 1950s, 1960s, and 1970s.

2. Ease of detection in animal models because of extensive virema.

3. Difficulties in growing primary human cells.

4. Results showing human sera with complement lysed animal retroviruses.