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Figure 3 | Retrovirology

Figure 3

From: The M50I polymorphic substitution in association with the R263K mutation in HIV-1 subtype B integrase increases drug resistance but does not restore viral replicative fitness

Figure 3

The effect of M50I with R263K on enzyme activity. Strand-transfer activity and enzyme efficiency of wild-type and mutant enzymes. A) Relative strand-transfer activity when varying the concentration of biotinylated target DNA. B) Vmax values. C) Km values. D) Enzyme efficiency as determined by the division of Vmax by Km. Error bars represent the standard errors of the means (SEM).

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Retrovirology

ISSN: 1742-4690

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