Discovery of prosimian and afrotherian foamy viruses and potential cross species transmissions amidst stable and ancient mammalian co-evolution

Table 1 Identification of foamy virus (FV)-like sequences in the aye-aye and Cape golden mole genome

Accession no.	FV genomic region	Position*	BLASTp best hit	Query cover	Max identity	E-value
Aye-aye ( *Daubentonia madagascariensis* )
AGTM011839603	(5′ truncated) 5′-LTR	3208..3318	N/A	N/A	N/A	N/A
	Primer binding site	3321..3338	N/A	N/A	N/A	N/A
	gag	3405..4654	CAA70074 Gag FFV	93%	37%	6E-72
AGTM012070104	gag	131..361	CAA70074 Gag FFV	93%	37%	6E-72
	pol	323..1247	AAF64414 Pol EFV	95%	48%	0.0
AGTM011519752		90..1996 (end)
AGTM010361255		1..635
AGTM010361255	(3′ truncated) env	520..2763	AFK85016 Env RhiFV	80%	42%	7E-115
Cape golden mole ( *Chrysochloris asiatica* )
AMDV01151999	(5′ truncated) pol	<615.. > 3534	AFX98084 Pol SFV	95%	47%	0.0
	env	<3464.. > 6371	AFR79245 Env BFV	96%	30%	5E-121
	bel1**	6338..6978	-	-	-	-

‘N/A’ = ‘Not applicable’.
*The nucleotide positions are with respect to the contig length and do not take insertion and deletion mutations into account.
**The similarity between ChrEFV Bel1 and other FV Bel1 proteins was determined by comparing the ChrEFV putative Bel1 protein against the Hidden Markov Model (HMM) of FV Bel1 proteins available in the GyDB (http://www.gydb.org/) (HMM profile: Bel1 spumaretroviridae; E: 0.24).

ISSN: 1742-4690