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Figure 1 | Retrovirology

Figure 1

From: Microarray analysis reveals global modulation of endogenous retroelement transcription by microbes

Figure 1

Characterization of RE-reporting probes and their corresponding probesets for the Affymetrix Mouse Genome 430v2 microarray platform. (A) Numbers of probesets (left axis) containing defined numbers of RE-reporting probes. The overall number of probesets containing RE-reporting probes was used to also express these values as a percentage of total (right axis). (B) Distribution of intragenic RE-reporting probes (including those within 1 kb of annotated genes) within the identified gene, expressed as a percentage of all RE-reporting probes within the platform. Locations are bins of percentage of gene length, to standardize for varying gene size. (C) mRNAs and their splicing patterns for two genes, represented by three probesets each, where a RE may be included in an alternate spice product (top) or within the canonical transcript (bottom). Track labeled with chromosome, location, and gene symbol shows the position and orientation of the reported RE (hashed arrow). Inclusion of the RE within an mRNA is denoted by its position either above (not included) or below (included) this track. Positions of probesets reporting the expression of the gene are shown below, with those in bold type containing RE-reporting probes. Data were obtained from the Ensembl Genome Browser.

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