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Table 4 Changes from baseline of CD4 + T cells and viral load by a longitudinal analysis.

From: The presence of anti-Tat antibodies in HIV-infected individuals is associated with containment of CD4+T-cell decay and viral load, and with delay of disease progression: results of a 3-year cohort study

Parameters

Estimate

95% confidence limits

P-value

CD4 + T cells/ÎĽl

   

Change per month in Anti-Tat Ab+

-1.6

-6.2; 3.0

0.4768

Change per month Anti-Tat Ab–

-8.9

-13.8; -3.9

0.0011

IgG anti-Env (log10 titers) anti-Tat Ab+

133.4

-130.0; 396.8

0.3070

IgG anti-Env (log10 titers) anti-Tat Ab–

150.0

-40.7; 340.6

0.1178

IgG anti-Gag (log10 titers) anti-Tat Ab+

-15.6

-141.6; 110.5

0.8014

IgG anti-Gag (log10 titers) anti-Tat Ab–

-56.0

-177.8; 65.9

0.3533

Viral load (log 10 copies/ÎĽl)

   

Change per month in Anti-Tat Ab+

0.005

-0.007; 0.018

0.3898

Change per month Anti-Tat Ab–

0.011

0.001; 0.021

0.0401

IgG anti-Env (log10 titers) anti-Tat Ab+

0.26

-0.64; 1.16

0.5560

IgG anti-Env (log10 titers) anti-Tat Ab–

0.08

-0.67; 0.83

0.8249

IgG anti-Gag (log10 titers) anti-Tat Ab+

-0.19

-0.57; 0.18

0.3006

IgG anti-Gag (log10 titers) anti-Tat Ab–

-0.15

-0.55; 0.26

0.4632

  1. Multivariate analysis for repeated measures of longitudinal samples from 41 individuals (random-effect regression model). Anti-Env and anti-Gag Abs were assessed at baseline and at 6, 18 and 36 months.