Skip to main content
Figure 5 | Retrovirology

Figure 5

From: Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits

Figure 5

Persistent fractions in neutralization assays. The infectivity of BG505.T332N pseudovirus was measured on Tzm-bl cells as luciferase activity (luminescence) after incubation with NAbs. The log [relative infectivity] is expressed on the y-axis as a function of the log NAb concentration [nM] on the x-axis. The data are fitted with a sigmoid function with variable slope and an unconstrained upper plateau; the lower plateau as a fitted parameter represents the persistent fraction, PF.

Back to article page