Figure 7From: Two M-T hook residues greatly improve the antiviral activity and resistance profile of the HIV-1 fusion inhibitor SC29EKIn vitro selection of HIV-1 resistant to fusion inhibitors. (A) Induction of resistant HIV-1 with SC29EK and MT-SC29EK; (B) Induction of resistant HIV-1 with SC22EK and MT-SC22EK. The molecular clone of HIV-1NL4–3 was passaged in the presence of 1.5-2 fold escalating concentrations of peptides. One culture is shown as a representative.Back to article page