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Table 1 Amino acid sequences (Nef126-143) of plasma HIV-1 in 46 patients

From: Switching and emergence of CTL epitopes in HIV-1 infection

Groupa Amino acid sequenceb Frequency (number)c
Consensus B NYTPGPGIRYPLTFGWCF  
135Y group   17.4% (8)
  ..................Y 2.2% (1)
  .............L.... 4.3% (2)
  .............L...Y 2.2% (1)
  .......V.......... 2.2% (1)
  C......T.....L.... 2.2% (1)
  .......T........P. 2.2% (1)
  .......T....C..... 2.2% (1)
135F group   76.1% (35)
  .........F........ 4.3% (2)
  C........F........ 2.2% (1)
  G........F........ 2.2% (1)
  .........F..C..... 2.2% (1)
  .......T.F........ 50.0% (23)
  C......T.F........ 2.2% (1)
  G......T.F........ 2.2% (1)
  .......V.F........ 8.7% (4)
  .......E.F..C..... 2.2% (1)
others   6.5% (3)
  .......V.L........ 4.3% (2)
  .......T.W........ 2.2% (1)
  1. aPatients were partitioned into three groups, Nef135Y (135Y), Nef135F (135F), or others, according to their amino acid information at the Nef135 position.
  2. bMiddle column shows amino acid sequence of the Nef126-143 region. The same amino acids as the subtype B consensus sequence are indicated by dots. Differences compared to the subtype B consensus sequence are indicated by the corresponding letters.
  3. cRight column indicates frequency (and number) of individuals exhibiting the stated sequence. Subtotal frequency (and number) of each group is italicized.