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Table 2 Ingenuity systems pathway analysis of genes found up-regulated by Tat and mutants iDC

From: HIV-1 Tat second exon limits the extent of Tat-mediated modulation of interferon-stimulated genes in antigen presenting cells

 

# Upregulated

# Downregulated

Infection mechanism (p-value)

Ad-TatSF2

67

9

3.30E-06

Ad-TatSF2A58T (SF13)

49

12

5.63E-05

Ad-TatHXB2

113

15

2.20E-12

Ad-TatSF21-72

205

31

1.57E-14

Ad-TatSF21-58

291

121

6.51E-16

Ad-TatSF2C20,25,34S

41

7

1.28E-02

Ad-TatSF2K28,50A

26

7

1.37E+00

Ad-TatSF2E86-92A

47

19

1.18E+01

IFN-α 100 U/ml

103

9

 

IFN-β 100 U/ml

248

49

 

IFN-γ 100 U/m

347

126

 

Type I IFNs

  

4.69E-10

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Retrovirology

ISSN: 1742-4690

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