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Figure 4 | Retrovirology

Figure 4

From: Trans-activation, post-transcriptional maturation, and induction of antibodies to HERV-K (HML-2) envelope transmembrane protein in HIV-1 infection

Figure 4

Anti-HERV-K (HML-2) TM and SU specific B-cell responses. A) The presence of HERV-K specific B-cells was detected at three time points from the same patient OP-115. CD19+ gated plots show the double population CD19 + tetramer + and the graphics represent the specific B-cells sub-populations. B) The study of the B-cell subset was based on CD27 and IgD extracellular expression. Memory cells (CD27+) were identified by their IgD expression; CD27+ IgD+: unswitched memory; CD27+ IgD-: switched memory. A Plasmablast is defined by the absence of IgD expression and a high expression of CD27.

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