Skip to main content
Figure 7 | Retrovirology

Figure 7

From: Live attenuated rubella vectors expressing SIV and HIV vaccine antigens replicate and elicit durable immune responses in rhesus macaques

Figure 7

Antibody response to replicating (A and B) and non-replicating (C and D) rubella vectors. (A) Macaque DCVV received a single dose of replicating vectors. Anti-Gag antibodies were detectable 2 weeks post immunization and they rose progressively by weeks 4 to 7. (B) Macaque V584 was primed three times with DNA vaccine, which elicited a good antibody response, and these titers rose substantially between 2 and 4 weeks after a single dose of live vectors. (C, D) Macaques CL6V and CL67 received three doses of non-replicating vectors. Antibodies were barely detectable after the first dose (5 weeks post immunization), but titers rose progressively after the second (4 weeks post immunization) and third doses (2 weeks post immunization), eventually reaching the same levels as a single dose of live vectors.

Back to article page

Retrovirology

ISSN: 1742-4690

Contact us