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Figure 3 | Retrovirology

Figure 3

From: Live attenuated rubella vectors expressing SIV and HIV vaccine antigens replicate and elicit durable immune responses in rhesus macaques

Figure 3

Rhesus macaque immunogenicity protocol. Macaques in group 1 received three doses of DNA vaccine, followed by a dose of rubella vectors at week 25 and a boost at week 57. Group 2 received DNA vaccine alone and were reserved for future studies. Group 3 received a series of three different rubella vectors, until the type 3 vectors gave a “take” in three out of three animals. They were boosted with two doses of DNA vaccine, starting at week 25. Group 4 control animals received rubella vaccine strain RA27/3 as an “empty” vector control, followed by two doses of control DNA plasmids, and a boost of rubella vectors at week 57.

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