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Table 3 Foxp3 and cytokine transcript levels at initiation (Before) and 30 days after (After) treatment with arsenic/IFN/zidovudine

From: The combination of arsenic, interferon-alpha, and zidovudine restores an “immunocompetent-like” cytokine expression profile in patients with adult T-cell leukemia lymphoma

Patient age

Foxp3 before

Foxp3 after

IL-10 before

IL-10 after

IL-4 before

IL-4 after

INF-γ before

INF-γ after

IL-2 before

IL-2 after

58

0

0

0

0

0

0

13

80

7

34

56

16

34

1372

66

2

0

4

28

9

22

60

163

15

70

6

0

0

4

16

1

6

47

4

11

69

4

3

4

5.9

18

17

64

53

43

138

34

4

12

10

11.8

124

8

67

72

12

8

0

0

2

0

0.3

16

0

0

36

197

62

2

0

7

1

4.3

17

3

32

46

6

13

2

3

0

0

0.8

8

3

43

63

12

50

14

11

3

3

7

57

1

12

51

53

28

927

112

19

3

5

22

1

3

68

12

6

23

6

1

1

6

62

1

4

60

20

11

2684

60

8

4

3

155

1

4

53

48

47

0

0

0

0

2

7

0

0

77

2

2

52

6

3

3

13

45

1

4

54

20

30

6584

4602

5

1

5

114

0

2

48

72

107

1011

286

3

2

6

25

10

45

  1. All values are expressed as percentage of human beta2-microglobulin used as internal control.