The combination of arsenic, interferon-alpha, and zidovudine restores an “immunocompetent-like” cytokine expression profile in patients with adult T-cell leukemia lymphoma

Table 2 Flow cytometry analysis of T cell surface markers at initiation (Before) and 30 days after (After) treatment with arsenic/IFN/zidovudine, SD, standard deviation

Patient age	CD4+ cell/μl		% CD4+ cells		CD8+ cell/μl		% CD8+ cells		%CD4+/ CD25+ cells
Patient age	Before	After	Before	After	Before	After	Before	After	Before	After
58	185710	90528	100	96	1857	1886	1	2	52	32
56	77040	2592	100	89	770	262	1	9	65	41
60	7020	3240	82	82	1320	1120	14	18	53	35
47	250	194	90	98	6318	3175	8	12	55	33
53	779	594	59	53	488	459	37	41	50	14
72	31142	4317	91	86	3080	703	9	14	44	25
36	5100	1584	93	90	5050	1095	7	10	48	42
46	4989	2072	85	67	3934	2360	15	33	58	22
63	4335	1061	80	42	765	523	20	28	41	7
51	1010	307	98	94	4269	1650	2	6	18	10
68	4989	1989	100	96	50	21	1	1	50	15
60	48370	15657	82	82	7980	2730	14	18	25	18
53	274	84	93	89	44984	13935	7	11	70	54
77	4469	1119	56	41	2873	764	36	28	52	25
54	1333	304	80	49	300	112	18	18	16	7
48	2160	2226	100	96	1	1	1	1	55	26
Mean			87	77			12	16	47	25
SD			14	22			12	12	15	14
P value			<0.01				<0.01		<0.001

P values indicate the significance level for the pairwise comparisons between “Before” and “after”.

ISSN: 1742-4690