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Figure 5 | Retrovirology

Figure 5

From: The combination of arsenic, interferon-alpha, and zidovudine restores an “immunocompetent-like” cytokine expression profile in patients with adult T-cell leukemia lymphoma

Figure 5

Treatment with arsenic/IFN/zidovudine increased IL-2 expression. A. IL-2 transcript levels in normal blood donors (n=10), healthy carriers of HTLV-I (n=10) and ATL patients (n=16) at initiation and 30 days after treatment with arsenic/IFN/zidovudine. Rectangles represent mean values. B. Mean and median IL-2 transcript levels of individual ATL patients at initiation and 30 days after treatment with arsenic/IFN/zidovudine. C, D. Relative expression of IL-2 transcripts after normalization to the number of CD4+CD25+ ATL cells. All values are expressed as percentage of human beta2-microglobulin used as internal control. *, **, *** indicate p values less than 0.05, 0.01 and 0.001 respectively.

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