Figure 7
From: HIV latency and integration site placement in five cell-based models
Acetylation and latency. (A) The number of ChIP-seq reads for H4K12ac, the histone mark with the lowest Fisher’s method p-value for correlation with latency, within 50,000 bases across the five samples. Integration sites (points) are spread in proportion to kernel density estimates. Horizontal lines indicate sample means where there was a significant difference (black) in means between silent/inducible and expressed provirus or no significant difference (grey). (B) The correlation (points) and its 95% confidence interval (vertical lines) between principal components of acetylation and silent/inducible status for each of the five samples. Red indicates correlations with a Bonferroni-corrected p-value >0.05.