Figure 2

Lasso regressions predicting latency. Misclassification error from cross validation for lasso regressions of silent/inducible status on genomic features as a function of λ, the regularization coefficient for the lasso regression, for all cell culture models combined (A) and each individual cell culture model (B-F). The number of variables included and size of coefficients in the model increases to the left. Whiskers show the standard error of mean misclassification error. Dashed vertical lines indicate the minimum misclassification error and the simplest model within one standard error. Dotted horizontal line indicates the misclassification error expected from random guessing.