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Figure 1 | Retrovirology

Figure 1

From: Heterogeneous susceptibility of circulating SIV isolate capsids to HIV-interacting factors

Figure 1

Capsid sequences of circulating SIV are highly variable. Alignment of matrix and capsid amino acid sequences of prototypic SIVmac251 and HIV-1 (pNL4-3) with those of SIV circulating in the wild, SIVmon-99CMCML1 accession No. AY340701 isolated from mona monkey (Cercopithecus mona); SIVgsn-99CM71 accession No. AF468658, from greater spot-nosed monkey (Cercopithecus nictitans); SIVmus-01CM1085 accession No. AY340700, from mustached monkey (Cercopithecus cephus), SIVmnd1, accession No. M27470, from mandrill (Mandrillus sphynx) and SIVcolCGU1 accession No. AF301156) from mantled guereza (Colobus guereza). Dots represent fully conserved residues and deletions are indicated with dashes. Arrows indicate the positions of the primers used to generate the chimeric GagPol constructs (MACA and CA). The beginning of CA is indicated by a star on top of the proline residue as well as the G89 and P90 residues; the CypA-binding loop is indicated on top of the corresponding residues.

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