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Figure 8 | Retrovirology

Figure 8

From: Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay

Figure 8

Initiation of reverse transcription was more rapid in E45A HIV-1 compared to WT, K203A, and 5Mut HIV-1. Early viral reverse transcripts (RU5) were measured by qPCR from TZM-bl cells infected with equal p24 levels of WT, E45A, K203A, and 5Mut HIV-1. Data represent the mean ± SEM of duplicates and are normalized for μg of total isolated DNA. Asterisks denote statistically significant p values (p < 0.05) between WT and each mutant at each time point. The graph is representative of 2 independent experiments.

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