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Table 1 EC 50 determination of EFdA and TDF in single cycle cell-based assays

From: Hypersusceptibility mechanism of Tenofovir-resistant HIV to EFdA

Virus EC50 ± SD (nM) (Fold change)
  EFdA TDF
WT 3.2 ± 0.7 32 ± 6
(1) (1)
K65R 1.3 ± 0.4 96 ± 3
  (0.4) (3)
  1. The data show “mean value ± standard deviation” obtained from the results of at least three independent experiments (P < 0.013). The relative increase in EC50 values against K65R virus compared with WT virus is given in parentheses.
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