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Table 1 EC 50 determination of EFdA and TDF in single cycle cell-based assays

From: Hypersusceptibility mechanism of Tenofovir-resistant HIV to EFdA

Virus

EC50 ± SD (nM) (Fold change)

 

EFdA

TDF

WT

3.2 ± 0.7

32 ± 6

(1)

(1)

K65R

1.3 ± 0.4

96 ± 3

 

(0.4)

(3)

  1. The data show “mean value ± standard deviation” obtained from the results of at least three independent experiments (P < 0.013). The relative increase in EC50 values against K65R virus compared with WT virus is given in parentheses.
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Retrovirology

ISSN: 1742-4690

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