Genistein monotherapy on Chinese rhesus macaques with chronic SIV infectionc. (A and B) Three Chinese rhesus macaques were chronically infected with SIVmac251. Each animal received 10 mg/kg of genistein orally for 12 weeks. The dynamics of the absolute CD4+ T cell count (A) and the percentages of CD4+ T cells (B) in peripheral blood were monitored. The percentage of CD4+ T cells were calculated by gating on total CD3+ T lymphocytes analyzed by flow cytometry. The absolute CD4+ T cell counts were generated from the calculation of percentages of CD4+ T cells, CD3+ T cells and lymphocytes from the complete blood count (CBC). (C) Plasma viral load before and after genistein monotherapy was also measured.