TY - JOUR AU - Moir, S. AU - Chun, T. W. AU - Fauci, A. S. PY - 2011 DA - 2011// TI - Pathogenic mechanisms of HIV disease JO - Annu Rev Pathol VL - 6 UR - https://doi.org/10.1146/annurev-pathol-011110-130254 DO - 10.1146/annurev-pathol-011110-130254 ID - Moir2011 ER - TY - JOUR AU - Chun, T. W. AU - Carruth, L. AU - Finzi, D. AU - Shen, X. AU - DiGiuseppe, J. A. AU - Taylor, H. AU - Hermankova, M. AU - Chadwick, K. AU - Margolick, J. AU - Quinn, T. C. PY - 1997 DA - 1997// TI - Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection JO - Nature VL - 387 UR - https://doi.org/10.1038/387183a0 DO - 10.1038/387183a0 ID - Chun1997 ER - TY - JOUR AU - Embretson, J. AU - Zupancic, M. AU - Beneke, J. AU - Till, M. AU - Wolinsky, S. AU - Ribas, J. L. AU - Burke, A. AU - Haase, A. T. PY - 1993 DA - 1993// TI - Analysis of human immunodeficiency virus-infected tissues by amplification and in situ hybridization reveals latent and permissive infections at single-cell resolution JO - Proc Natl Acad Sci USA VL - 90 UR - https://doi.org/10.1073/pnas.90.1.357 DO - 10.1073/pnas.90.1.357 ID - Embretson1993 ER - TY - JOUR AU - Douek, D. C. AU - Roederer, M. AU - Koup, R. A. PY - 2009 DA - 2009// TI - Emerging concepts in the immunopathogenesis of AIDS JO - Annu Rev Med VL - 60 UR - https://doi.org/10.1146/annurev.med.60.041807.123549 DO - 10.1146/annurev.med.60.041807.123549 ID - Douek2009 ER - TY - JOUR AU - Grossman, Z. AU - Meier-Schellersheim, M. AU - Sousa, A. E. AU - Victorino, R. M. AU - Paul, W. E. PY - 2002 DA - 2002// TI - CD4+ T-cell depletion in HIV infection: are we closer to understanding the cause? JO - Nat Med VL - 8 UR - https://doi.org/10.1038/nm0402-319 DO - 10.1038/nm0402-319 ID - Grossman2002 ER - TY - JOUR AU - Finkel, T. H. AU - Tudor-Williams, G. AU - Banda, N. K. AU - Cotton, M. F. AU - Curiel, T. AU - Monks, C. AU - Baba, T. W. AU - Ruprecht, R. M. AU - Kupfer, A. PY - 1995 DA - 1995// TI - Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes JO - Nat Med VL - 1 UR - https://doi.org/10.1038/nm0295-129 DO - 10.1038/nm0295-129 ID - Finkel1995 ER - TY - JOUR AU - Igarashi, T. AU - Brown, C. R. AU - Byrum, R. A. AU - Nishimura, Y. AU - Endo, Y. AU - Plishka, R. J. AU - Buckler, C. AU - Buckler-White, A. AU - Miller, G. AU - Hirsch, V. M. AU - Martin, M. A. PY - 2002 DA - 2002// TI - Rapid and irreversible CD4+ T-cell depletion induced by the highly pathogenic simian/human immunodeficiency virus SHIV(DH12R) is systemic and synchronous JO - J Virol VL - 76 UR - https://doi.org/10.1128/JVI.76.1.379-391.2002 DO - 10.1128/JVI.76.1.379-391.2002 ID - Igarashi2002 ER - TY - JOUR AU - Miura, Y. AU - Misawa, N. AU - Maeda, N. AU - Inagaki, Y. AU - Tanaka, Y. AU - Ito, M. AU - Kayagaki, N. AU - Yamamoto, N. AU - Yagita, H. AU - Mizusawa, H. AU - Koyanagi, Y. PY - 2001 DA - 2001// TI - Critical contribution of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to apoptosis of human CD4+ T cells in HIV-1-infected hu-PBL-NOD-SCID mice JO - J Exp Med VL - 193 UR - https://doi.org/10.1084/jem.193.5.651 DO - 10.1084/jem.193.5.651 ID - Miura2001 ER - TY - JOUR AU - Monceaux, V. AU - Estaquier, J. AU - Fevrier, M. AU - Cumont, M. C. AU - Riviere, Y. AU - Aubertin, A. M. AU - Ameisen, J. C. AU - Hurtrel, B. PY - 2003 DA - 2003// TI - Extensive apoptosis in lymphoid organs during primary SIV infection predicts rapid progression towards AIDS JO - AIDS VL - 17 UR - https://doi.org/10.1097/00002030-200307250-00002 DO - 10.1097/00002030-200307250-00002 ID - Monceaux2003 ER - TY - JOUR AU - Phenix, B. N. AU - Badley, A. D. PY - 2002 DA - 2002// TI - Influence of mitochondrial control of apoptosis on the pathogenesis, complications and treatment of HIV infection JO - Biochimie VL - 84 UR - https://doi.org/10.1016/S0300-9084(02)01378-0 DO - 10.1016/S0300-9084(02)01378-0 ID - Phenix2002 ER - TY - JOUR AU - Hazenberg, M. D. AU - Hamann, D. AU - Schuitemaker, H. AU - Miedema, F. PY - 2000 DA - 2000// TI - T cell depletion in HIV-1 infection: how CD4+ T cells go out of stock JO - Nat Immunol VL - 1 UR - https://doi.org/10.1038/79724 DO - 10.1038/79724 ID - Hazenberg2000 ER - TY - JOUR AU - Ahr, B. AU - Robert-Hebmann, V. AU - Devaux, C. AU - Biard-Piechaczyk, M. PY - 2004 DA - 2004// TI - Apoptosis of uninfected cells induced by HIV envelope glycoproteins JO - Retrovirology VL - 1 UR - https://doi.org/10.1186/1742-4690-1-12 DO - 10.1186/1742-4690-1-12 ID - Ahr2004 ER - TY - JOUR AU - Li, H. AU - Pauza, C. D. PY - 2011 DA - 2011// TI - HIV envelope-mediated, CCR5/alpha4beta7-dependent killing of CD4-negative gammadelta T cells which are lost during progression to AIDS JO - Blood VL - 118 UR - https://doi.org/10.1182/blood-2011-05-356535 DO - 10.1182/blood-2011-05-356535 ID - Li2011 ER - TY - JOUR AU - Li, H. AU - Pauza, C. D. PY - 2012 DA - 2012// TI - The alpha4beta7 integrin binds HIV envelope but does not mediate bystander killing of gammadelta T cells JO - Blood VL - 120 UR - https://doi.org/10.1182/blood-2012-03-420117 DO - 10.1182/blood-2012-03-420117 ID - Li2012 ER - TY - JOUR AU - Medders, K. E. AU - Sejbuk, N. E. AU - Maung, R. AU - Desai, M. K. AU - Kaul, M. PY - 2010 DA - 2010// TI - Activation of p38 MAPK is required in monocytic and neuronal cells for HIV glycoprotein 120-induced neurotoxicity JO - J Immunol VL - 185 UR - https://doi.org/10.4049/jimmunol.0902535 DO - 10.4049/jimmunol.0902535 ID - Medders2010 ER - TY - JOUR AU - Fiala, M. AU - Murphy, T. AU - MacDougall, J. AU - Yang, W. AU - Luque, A. AU - Iruela-Arispe, L. AU - Cashman, J. AU - Buga, G. AU - Byrns, R. E. AU - Barbaro, G. AU - Arthos, J. PY - 2004 DA - 2004// TI - HAART drugs induce mitochondrial damage and intercellular gaps and gp120 causes apoptosis JO - Cardiovasc Toxicol VL - 4 UR - https://doi.org/10.1385/CT:4:4:327 DO - 10.1385/CT:4:4:327 ID - Fiala2004 ER - TY - JOUR AU - Vlahakis, S. R. AU - Villasis-Keever, A. AU - Gomez, T. S. AU - Bren, G. D. AU - Paya, C. V. PY - 2003 DA - 2003// TI - Human immunodeficiency virus-induced apoptosis of human hepatocytes via CXCR4 JO - J Infect Dis VL - 188 UR - https://doi.org/10.1086/379738 DO - 10.1086/379738 ID - Vlahakis2003 ER - TY - JOUR AU - Vashistha, H. AU - Husain, M. AU - Kumar, D. AU - Singhal, P. C. PY - 2009 DA - 2009// TI - Tubular cell HIV-1 gp120 expression induces caspase 8 activation and apoptosis JO - Ren Fail VL - 31 UR - https://doi.org/10.1080/08860220902780101 DO - 10.1080/08860220902780101 ID - Vashistha2009 ER - TY - JOUR AU - Kanmogne, G. D. AU - Primeaux, C. AU - Grammas, P. PY - 2005 DA - 2005// TI - Induction of apoptosis and endothelin-1 secretion in primary human lung endothelial cells by HIV-1 gp120 proteins JO - Biochem Biophys Res Commun VL - 333 UR - https://doi.org/10.1016/j.bbrc.2005.05.198 DO - 10.1016/j.bbrc.2005.05.198 ID - Kanmogne2005 ER - TY - JOUR AU - Lin, H. AU - Chen, W. AU - Luo, L. AU - Wu, C. AU - Wang, Q. AU - Liu, Y. PY - 2011 DA - 2011// TI - Cytotoxic effect of HIV-1 gp120 on primary cultured human retinal capillary endothelial cells JO - Mol Vis VL - 17 ID - Lin2011 ER - TY - JOUR AU - Trushin, S. A. AU - Algeciras-Schimnich, A. AU - Vlahakis, S. R. AU - Bren, G. D. AU - Warren, S. AU - Schnepple, D. J. AU - Badley, A. D. PY - 2007 DA - 2007// TI - Glycoprotein 120 binding to CXCR4 causes p38-dependent primary T cell death that is facilitated by, but does not require cell-associated CD4 JO - J Immunol VL - 178 UR - https://doi.org/10.4049/jimmunol.178.8.4846 DO - 10.4049/jimmunol.178.8.4846 ID - Trushin2007 ER - TY - JOUR AU - Vlahakis, S. R. AU - Algeciras-Schimnich, A. AU - Bou, G. AU - Heppelmann, C. J. AU - Villasis-Keever, A. AU - Collman, R. G. AU - Paya, C. V. PY - 2001 DA - 2001// TI - Chemokine-receptor activation by env determines the mechanism of death in HIV-infected and uninfected T lymphocytes JO - J Clin Invest VL - 107 UR - https://doi.org/10.1172/JCI11109 DO - 10.1172/JCI11109 ID - Vlahakis2001 ER - TY - JOUR AU - Jacotot, E. AU - Krust, B. AU - Callebaut, C. AU - Laurent-Crawford, A. G. AU - Blanco, J. AU - Hovanessian, A. G. PY - 1997 DA - 1997// TI - HIV-1 envelope glycoproteins-mediated apoptosis is regulated by CD4 dependent and independent mechanisms JO - Apoptosis VL - 2 UR - https://doi.org/10.1023/A:1026435625144 DO - 10.1023/A:1026435625144 ID - Jacotot1997 ER - TY - JOUR AU - Holm, G. H. AU - Zhang, C. AU - Gorry, P. R. AU - Peden, K. AU - Schols, D. AU - De Clercq, E. AU - Gabuzda, D. PY - 2004 DA - 2004// TI - Apoptosis of bystander T cells induced by human immunodeficiency virus type 1 with increased envelope/receptor affinity and coreceptor binding site exposure JO - J Virol VL - 78 UR - https://doi.org/10.1128/JVI.78.9.4541-4551.2004 DO - 10.1128/JVI.78.9.4541-4551.2004 ID - Holm2004 ER - TY - JOUR AU - Trushin, S. A. AU - Algeciras-Schimnich, A. AU - Vlahakis, S. R. AU - Bren, G. D. AU - Warren, S. AU - Schnepple, D. J. AU - Badley, A. D. PY - 2007 DA - 2007// TI - Glycoprotein 120 binding to CXCR4 causes p38-dependent primary T cell death that is facilitated by, but does not require cell-associated CD4 JO - J Immunol VL - 178 UR - https://doi.org/10.4049/jimmunol.178.8.4846 DO - 10.4049/jimmunol.178.8.4846 ID - Trushin2007 ER - TY - JOUR AU - Biard-Piechaczyk, M. AU - Robert-Hebmann, V. AU - Richard, V. AU - Roland, J. AU - Hipskind, R. A. AU - Devaux, C. PY - 2000 DA - 2000// TI - Caspase-dependent apoptosis of cells expressing the chemokine receptor CXCR4 is induced by cell membrane-associated human immunodeficiency virus type 1 envelope glycoprotein (gp120) JO - Virology VL - 268 UR - https://doi.org/10.1006/viro.1999.0151 DO - 10.1006/viro.1999.0151 ID - Biard-Piechaczyk2000 ER - TY - JOUR AU - Blanco, J. AU - Barretina, J. AU - Henson, G. AU - Bridger, G. AU - De Clercq, E. AU - Clotet, B. AU - Este, J. A. PY - 2000 DA - 2000// TI - The CXCR4 antagonist AMD3100 efficiently inhibits cell-surface-expressed human immunodeficiency virus type 1 envelope-induced apoptosis JO - Antimicrob Agents Chemother VL - 44 UR - https://doi.org/10.1128/AAC.44.1.51-56.2000 DO - 10.1128/AAC.44.1.51-56.2000 ID - Blanco2000 ER - TY - JOUR AU - Crotty, S. PY - 2011 DA - 2011// TI - Follicular helper CD4 T cells (TFH) JO - Annu Rev Immunol VL - 29 UR - https://doi.org/10.1146/annurev-immunol-031210-101400 DO - 10.1146/annurev-immunol-031210-101400 ID - Crotty2011 ER - TY - JOUR AU - Oh, S. K. AU - Cruikshank, W. W. AU - Raina, J. AU - Blanchard, G. C. AU - Adler, W. H. AU - Walker, J. AU - Kornfeld, H. PY - 1992 DA - 1992// TI - Identification of HIV-1 envelope glycoprotein in the serum of AIDS and ARC patients JO - J Acquir Immune Defic Syndr VL - 5 UR - https://doi.org/10.1097/00126334-199203000-00005 DO - 10.1097/00126334-199203000-00005 ID - Oh1992 ER - TY - JOUR AU - Cummins, N. W. AU - Rizza, S. A. AU - Badley, A. D. PY - 2010 DA - 2010// TI - How much gp120 is there? JO - J Infect Dis VL - 201 UR - https://doi.org/10.1086/651434 DO - 10.1086/651434 ID - Cummins2010 ER - TY - JOUR AU - Pantaleo, G. AU - Graziosi, C. AU - Demarest, J. F. AU - Butini, L. AU - Montroni, M. AU - Fox, C. H. AU - Orenstein, J. M. AU - Kotler, D. P. AU - Fauci, A. S. PY - 1993 DA - 1993// TI - HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease JO - Nature VL - 362 UR - https://doi.org/10.1038/362355a0 DO - 10.1038/362355a0 ID - Pantaleo1993 ER - TY - JOUR AU - Fox, C. H. AU - Tenner-Racz, K. AU - Racz, P. AU - Firpo, A. AU - Pizzo, P. A. AU - Fauci, A. S. PY - 1991 DA - 1991// TI - Lymphoid germinal centers are reservoirs of human immunodeficiency virus type 1 RNA JO - J Infect Dis VL - 164 UR - https://doi.org/10.1093/infdis/164.6.1051 DO - 10.1093/infdis/164.6.1051 ID - Fox1991 ER - TY - JOUR AU - Sunila, I. AU - Vaccarezza, M. AU - Pantaleo, G. AU - Fauci, A. S. AU - Orenstein, J. M. PY - 1997 DA - 1997// TI - gp120 is present on the plasma membrane of apoptotic CD4 cells prepared from lymph nodes of HIV-1-infected individuals: an immunoelectron microscopic study JO - AIDS VL - 11 UR - https://doi.org/10.1097/00002030-199701000-00005 DO - 10.1097/00002030-199701000-00005 ID - Sunila1997 ER - TY - JOUR AU - Lindqvist, M. AU - van Lunzen, J. AU - Soghoian, D. Z. AU - Kuhl, B. D. AU - Ranasinghe, S. AU - Kranias, G. AU - Flanders, M. D. AU - Cutler, S. AU - Yudanin, N. AU - Muller, M. I. PY - 2012 DA - 2012// TI - Expansion of HIV-specific T follicular helper cells in chronic HIV infection JO - J Clin Invest VL - 122 UR - https://doi.org/10.1172/JCI64314 DO - 10.1172/JCI64314 ID - Lindqvist2012 ER - TY - JOUR AU - Lane, H. C. AU - Masur, H. AU - Edgar, L. C. AU - Whalen, G. AU - Rook, A. H. AU - Fauci, A. S. PY - 1983 DA - 1983// TI - Abnormalities of B-cell activation and immunoregulation in patients with the acquired immunodeficiency syndrome JO - N Engl J Med VL - 309 UR - https://doi.org/10.1056/NEJM198308253090803 DO - 10.1056/NEJM198308253090803 ID - Lane1983 ER - TY - JOUR AU - De Milito, A. AU - Nilsson, A. AU - Titanji, K. AU - Thorstensson, R. AU - Reizenstein, E. AU - Narita, M. AU - Grutzmeier, S. AU - Sonnerborg, A. AU - Chiodi, F. PY - 2004 DA - 2004// TI - Mechanisms of hypergammaglobulinemia and impaired antigen-specific humoral immunity in HIV-1 infection JO - Blood VL - 103 UR - https://doi.org/10.1182/blood-2003-07-2375 DO - 10.1182/blood-2003-07-2375 ID - De Milito2004 ER - TY - JOUR AU - Petrovas, C. AU - Yamamoto, T. AU - Gerner, M. Y. AU - Boswell, K. L. AU - Wloka, K. AU - Smith, E. C. AU - Ambrozak, D. R. AU - Sandler, N. G. AU - Timmer, K. J. AU - Sun, X. PY - 2012 DA - 2012// TI - CD4 T follicular helper cell dynamics during SIV infection JO - J Clin Invest VL - 122 UR - https://doi.org/10.1172/JCI63039 DO - 10.1172/JCI63039 ID - Petrovas2012 ER - TY - JOUR AU - Doitsh, G. AU - Cavrois, M. AU - Lassen, K. G. AU - Zepeda, O. AU - Yang, Z. AU - Santiago, M. L. AU - Hebbeler, A. M. AU - Greene, W. C. PY - 2010 DA - 2010// TI - Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue JO - Cell VL - 143 UR - https://doi.org/10.1016/j.cell.2010.11.001 DO - 10.1016/j.cell.2010.11.001 ID - Doitsh2010 ER -