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Figure 3 | Retrovirology

Figure 3

From: TLR-4 engagement of dendritic cells confers a BST-2/tetherin-mediated restriction of HIV-1 infection to CD4+T cells across the virological synapse

Figure 3

LPS-induced relocalization of BST-2/tetherin in HIV-containing tetraspanin-enriched compartment. (A) Confocal immunofluorescence analysis of HIV-Gag (green), BST-2/tetherin (red) and CD81 (blue) of DC pre-treated (or not) with IFN-α or LPS and left uninfected or challenged with HIV-WT or HIV-ΔVpu for 3 days. Data are representative of four independent experiments. Scale bars correspond to 5 μm. (B) Graphs represent the quantification of BST-2/tetherin and CD81 co-localisation with HIV-Gag from at least 24 cells per condition from 3 independent experiments.

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Retrovirology

ISSN: 1742-4690

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