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Table 1 Proviral DNA loads in tissues

From: Conditionally-live attenuated SIV upregulates global T effector memory cell frequency under replication permissive conditions

Animal No.

SIV DNA copies /105MNC

SlV-rtTA∆nef

SlV∆nef

Dox withdrawn

Dox maintained

E62

E64

E69

E72

E74

E78

PBMC

<1a

<1

1.37

<1

2.59

2.63

Spleen

1.79

2.47

10.3

8.02

95.0

25.83

Peripheral LNb

<1

1.46

12.1

88.4

50.1

50.3

Thymus

<1

<1

<1

<1

NDc

ND

Mesenteric LN

<1

4.93

4.61

1.92

178.2

120.3

Small intestine

<1

<1

<1

4.27

3.87

7.38

Large intestine

1.31

2.58

4.4

2.68

1.88

12.8

  1. a < indicates below the limit of detection; bLN lymph node, cND not done.
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Retrovirology

ISSN: 1742-4690

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