From: Within-host and between-host evolutionary rates across the HIV-1 genome
i | Cut the genome sequences into segments |
ii | Remove recombining sequences |
iii | Check for the existence of molecular clock signal in the data |
iv | Balancing datasets (to maximise clock-likeness) |
v | Select the most appropriate substitution model |
vi | Compare molecular clock models and coalescent models |
vii | Run the bayesian phylogeny inference package (BEAST) |
viii | Analyse substitution rates on internal and external branches |