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Table 3 Method steps

From: Within-host and between-host evolutionary rates across the HIV-1 genome

i

Cut the genome sequences into segments

ii

Remove recombining sequences

iii

Check for the existence of molecular clock signal in the data

iv

Balancing datasets (to maximise clock-likeness)

v

Select the most appropriate substitution model

vi

Compare molecular clock models and coalescent models

vii

Run the bayesian phylogeny inference package (BEAST)

viii

Analyse substitution rates on internal and external branches