Figure 1
From: Platelet activation suppresses HIV-1 infection of T cells
Analysis of CD62P and C-type lectin expression on platelets. (A) CD62P expression on activated and resting platelets. Platelets maintained resting by treatment with PGE1 (R-PLT), activated by exposure to TRAP (A-PLT) or platelets left untreated (PLT) were analyzed by flow cytometry for surface expression of CD62P. The geometric mean channel fluorescence was measured. The results present the average of three experiments with samples from two different donors. Error bars indicate standard deviation (SD). (B) Lectin expression on platelets. Untreated platelets were stained with anti-DC-SIGN, -MR and -LSECtin antibodies (grey histograms) or isotype-matched control antibodies (black lines) and analyzed by flow cytometry. Unstained platelets are depicted in black filled histograms. The results are representative of three independent experiments.