Figure 6

GFP-TM1 incorporation reduces viral entry mediated by JRFL ΔCT Env. Titrating amounts of GFP-TM1 were incorporated in immature (hollow diamond) or mature (hollow circle) HIV-1 bearing JRFL ΔCT Env. Immature (solid diamond) or mature (solid circle) JRFL WT viruses were also generated within the same batch as controls. CT incorporation levels (representing GFP-TM1 or WT Env) are normalized to those of the corresponding immature or mature viruses with 100% GFP-TM1 plasmid input. Specific viral entry activity is normalized to those of the corresponding immature or mature ΔCT viruses with no GFP-TM1. Error bars indicate the SEM.