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Figure 3 | Retrovirology

Figure 3

From: The V86M mutation in HIV-1 capsid confers resistance to TRIM5α by abrogation of cyclophilin A-dependent restriction and enhancement of viral nuclear import

Figure 3

CsA dose-dependent analysis. TE671 cells (A) and Sup-T1 cells (B) expressing R332G-R335G TRIM5αhu or transduced with the “empty” vector were challenged with WT or V86M HIV-1NL-GFP in the presence of increasing concentrations of CsA. Virus doses were adjusted so that approximately 1% of cells were infected in the absence of CsA. The percentages of infected cells were determined two days later as before and results are shown as –fold increases relative to the relevant no-drug controls.

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Retrovirology

ISSN: 1742-4690

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